Gastroenterology Education and CPD for trainees and specialists

1. Which one of the following statements regarding IBD associated with primary sclerosing cholangitis (PSC) is false?

1. 60-80% of PSC patients will have IBD
2. Less than 10% of IBD patients will have PSC
3. Rectal sparing is unsual in IBD associated with PSC
4. All patients with PSC should have colonoscopy at diagnosis.
5. Colorectal cancer in IBD associated with PSC is typically right sided

2. Which one of the following statements regarding treatment of PSC is false?

1. UDCA in PSC is recommended.
2. Unique liver transplant indications for patients with PSC include intractable pruritus
3. Surveillance colonoscopy at one to two year intervals from the time of diagnosis of PSC in patients with colitis is recommended
4. In all patients with possible PSC, serum IgGg 4 levels should be measured to exclude IgG 4-associated sclerosing cholangitis.
5. Periductal concentric (“onion-skin”) ﬁbrosis is a classic histopathologic ﬁnding of PSC

3. Which one of the following statements regarding treatment of PSC is true?

1. Primary sclerosing cholangitis (PSC) is seen in HIV
2. Liver biopsy might be needed if large duct PSC is suspected
3. A dominant stricture can be assumed to be benign in event of negative MRI scan, CA 19-9 value <130 U/mL, and negative cytology.
4. .Colorectal neoplasia associated with PSC appears to have a predilection for the distal colon, with up to 76% having a left-sided distribution.
5. The incidence of cholangiocarcinoma in PSC is not any different from general population

Gastroenterology training and education

MCQ On Primary Sclerosing Cholangitis

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