Upper GI Crohn’s disease
Discuss upper GI Crohn’s disease?
- Oral Crohn’s disease
- Aphthous ulcers are the most common feature of Crohn’s disease in the oral cavity.
- Oral lesions parallel intestinal disease activity and respond to treatment directed at intestinal disease.
- Topical hydrocortisone or topical sucralfate may provide symptomatic relief.
- Gastroduodenal Crohn’s disease
- It is rare and occurs in association with intestinal disease.
- Gastric antrum and duodenum are most commonly affected.
- The symptoms include epigastric pain, nausea and vomiting.
- PPI may provide symptomatic relief. Pentasa is partly released in the proximal small bowel and may theoretically help in duodenal disease.
- However, steroid is usually necessary and is effective. Immunomodulators may be needed.
