Units: Conventional Standard

Creatinine Clearance (Cockcroft-Gault Equation)

Is patient female? Yes
Age years old
Weight
kg
Serum creatinine
μmol/L
Creatinine Clearance mL/min 

Short note:

Estimated creatinine clearance rate (eCCr) is calculated using Cockcroft-Gault formula

When serum creatinine is measured in mg/dL (conventional):

When serum creatinine is measured in μmol/L (SI) :


Where Constant is 1.23 for men and 1.04 for women.

Creatinine-based equations should be used with caution in patients with very low muscle mass (like cachectic or cirrhotic patients). These patients will have a much lower creatinine excretion rate than predicted by the equations above.

Further, this formula does not correct for race. It is known that African Americans have a higher muscle mass than Caucasians; hence, African Americans will have a higher serum creatinine level at any level of creatinine clearance.

BNF renal impairment bandings:

CrCl Level of renal impairment
50-20ml/min Mild
20-10ml/min Moderate
Less than 10ml/min Severe

For dose reduction of antibiotic in renal impairment:

www.nuh.nhs.uk

Disclaimer:
The calculators allow you to enter patient specific information to calculate a simple score. All information is provided for educational purposes only. This information is not intended to replace clinical judgement. All calculations must be rechecked and should not be used alone to guide patient care. The user assumes sole responsibility for any decisions or action taken based on the information contained here.